The Truth About Antibiotic Resistance
When a bacterial infection becomes resistant to antibiotics, doctors talk about resilience. It makes diseases more challenging to treat and increases the risk of pneumonia, childbirth, and abrasions, suddenly becoming fatal.
The researchers open new fronts
Medical researchers are working on high pressure to develop new forms of treatment that can support the persistent antibiotic.
Borrowed antibodies support your own. When bacteria infect the body, it develops antibodies. But the development takes days or weeks. American scientists are working to develop a nasal spray with synthetic antibodies. As a template, they use natural antibodies from, among other things, llamas.
Good bacteria fight infections. The companies SciBac in California and Vedanta Biosciences in Massachusetts are both working to stop infections of Clostridium difficile, which causes life-threatening diarrhea. The weapon is the good bacteria that can be swallowed in pill form and which knock out Clostridium difficile in the intestinal system.
Double dose increases efficiency. European molecular biologists have tested 3000 double doses with two antibiotic types or one antibiotic type and a so-called booster. For example, as a booster, vanilla has proven to be surprisingly effective against certain types of resistant bacteria.
“WE WILL SOON HAVE NO FUNCTIONING ANTIBIOTICS”
– PARTIALLY TRUE
Drug manufacturers have difficulty developing new preparations at the same rate as the bacteria growing resistance. Today, the bacteria have taken over in the coat armor.
Before the 1950s, even small ulcers in the skin could be fatal if infected. Since then, penicillin alone has saved over 200 million lives, but bacteria have gradually become less sensitive to treatment.
The phenomenon is called resistance and is due to the bacteria developing the ability to pump out antibiotics through the cell wall or to form enzymes that can break down the antibiotic.
Bacteria become invulnerable to antibiotics
Natural mutations make a bacterium resistant (blue) to antibiotics that kill all other bacteria (red).
Resistant bacteria multiply
Without competition, the resistant bacterium can multiply freely and make the entire colony resistant.
The resistant bacteria share their DNA with other species of bacteria and thereby spread the resistance.
Over the past 50 years, only three completely new classes of antibiotics have been discovered.
During the same period, the bacteria have developed resistance to all known preparations – except the very latest, odilorhabdin, which is not yet on the market. Therefore, doctors are talking about a new medical middle age where infections run amok and cannot be treated.
The researchers estimate that the hunt for new antibiotics must be prioritized internationally. They suggest a salary of well over EUR 10 billion as a spur for the pharmaceutical companies to fight hard to develop new antibiotics.
“RESISTANCE IS NOT A PROBLEM IN EUROPE”
Antibiotic resistance is as much a problem in the EU as flu, TBC, and HIV / AIDS. The ECDC, the European Center for Disease Prevention and Control, estimates that 672,000 Europeans suffer from multi-resistant bacteria every year.
The number of Europeans who die each year as a result of multi-resistant infections is 33,000.
“ONLY BACTERIA BECOME RESISTANT”
One of the most infectious multi-resistant organisms on the planet is not a bacterium but a yeast fungus.
Candida Auris was found for the first time in 2009 in the ear of a Japanese woman. Candida Auris can easily withstand traditional means of fungi and, in 20 percent of cases, even the most advanced.
Doctor Tom Chiller, who heads the fungal research unit at the CDC (Centers for Disease Control and Prevention), says Candida Auris is “more contagious than Ebola”.